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GREETINGS
Asher Kimchi, USA
Founder and Chairman
International Academy of Cardiology
14th World Congress on Heart Disease

Jeffrey S. Borer, USA
Chairman, Scientific Executive Committee
Chairman, Section of Valvular Heart Disease
International Academy of Cardiology
14th World Congress on Heart Disease

John A. Elefteriades, USA
Member, Scientific Executive Committee
Chairman, Section of Cardiovascular Surgery
International Academy of Cardiology
14th World Congress on Heart Disease

Marcos A. Rossi, Brazil
Member, Scientific Executive Committee
Chairman, Section of  
International Academy of Cardiology
14th World Congress on Heart Disease

Pawan K. Singal, Canada
Member, Scientific Executive Committee
Chairman, Section of  
International Academy of Cardiology
14th World Congress on Heart Disease

PRESENTATION OF 2008 AWARDS
Jeffrey S. Borer, USA

WOMEN AND HEART DISEASE IN THE POST-WHI ERA (Invited Lecture)
E.L. Barrett-Connor, University of California, San Diego, CA, USA

PL:01      Plenary Session
NEW THERAPEUTIC TARGETS IN CARDIOVASCULAR MEDICINE
Chairpersons:  C. Patterson, Chapel Hill, NC, USA

INHIBITION OF PHOSPHOLIPASES: A NEW STRATEGY TO TREAT ATHEROSCLEROSIS AND ITS CLINICAL COMPLICATIONS? (Invited Lecture)
W. Koenig, University of Ulm, Ulm, Germany

AN UNAPPRECIATED ROLE FOR UBIQUITIN LIGASES IN EXPERIMENTAL CARDIAC HYPERTROPHY (Invited Lecture) 
C. Patterson, University of North Carolina, Chapel Hill, NC, USA

RENIN INHIBITION: A NOVEL APPROACH TO BLOOD PRESSURE CONTROL AND ORGAN PROTECTION (Invited Lecture)
A.H.J. Danser, Erasmus Medical Center, Rotterdam, The Netherlands

CARDIOPROTECTIVE ROLE OF SODIUM THIOSULFATE ON CHRONIC HEART FAILURE BY MODULATING ENDOGENOUS H2S GENERATION (Invited Lecture)
S.C. Tyagi, University of Louisville, Louisville, KY, USA

ROLE OF SARCOPLASMIC RETICULUM IN INCREASING INTRACELLULAR CA2+ DUE TO NA+-K+ ATPASE INHIBITION BY OUABAIN (Invited Lecture)
H.K. Saini-Chohan, N.S. Dhalla, University of Manitoba, Winnipeg, MB, Canada

FINDING AND VALIDATING NEW TARGETS FOR HEART FAILURE TREATMENT (Invited Lecture)
B.C. Blaxall, University of Rochester Medical Center, Rochester, NY, USA

PL:02       Plenary Session
WHAT’S NEW IN CARDIOMYOPATHIES
Chairpersons: K. Chatterjee, San Francisco, CA, USA
                     M.A. Rossi, Ribeirao Preto, SP, Brazil

THE ROLE OF THE INNATE IMMUNE RESPONSE IN PROTECTING AGAINST INFECTION OF THE HEART (Invited Lecture)
N.E. Bowles, G. Vallejo, University of Utah, Salt Lake City, UT, USA

CARDIOVASCULAR EFFECTS OF CHRONIC, SUBCLINICAL EXPOSURE TO LIPOPOLYSACCHARIDE (Invited Lecture)
W.Y.W. Lew, University of California, San Diego, CA, USA

SEPSIS AND THE HEART (Invited Lecture)
M.A. Rossi, M.R. Celes, D. Torres-Duena, E.C. Campos, C.M. Prado, F.Q. Cunha, University of Sao Paulo, Ribeirao Preto, SP, Brazil

A UNIQUE CLINICAL, GENETIC AND MORPHOLOGICAL FEATURES IN HUMAN MITOCHONDRIAL CARDIOMYOPATHY (Invited Lecture)
T. Toyo-Oka, H. Hatakeyama, S. Kostin, J. Schaper, Tohoku University, Sendai, Japan

DILATED CARDIOMYOPATHY: VARIOUS ETIOLOGIES AND OUTCOME (Invited Lecture)
N.N. Kipshidze, National Center of Therapy, Tbilisi, Georgia

S21         Session
ACUTE CORONARY SYNDROMES, ACUTE MI, INTERVENTIONAL CARDIOLOGY
Chairpersons:   M.R. Movahed, Tuscon, AZ, USA
                       A.T. Weiss, Jerusalem, Israel
 

INTRAGRAFT ADMINISTRATION OF ABCIXIMAB AND VERAPAMIL COMBINED WITH DIRECT STENTING PREVENTS SLOW-FLOW AND NO-REFLOW PHENOMENON IN SAPHENOUS VEIN GRAFT PERCUTANEOUS CORONARY INTERVENTION
S. Sharma, J.A. Lardizabal, A. Antonescu, B. Bhambi, W. Nyitray, K. Desai, T. Ishimori, University Hospital Lewisham, London, UK

EARLY INVASIVE THERAPY VERSUS CONSERVATIVE MANAGEMENT IN ACUTE CORONARY SYNDROMES: A LONG-TERM ANALYSIS 
D.J. Kumbhani, A.A. Bavry, A.N. Rassi, D.L. Bhatt, A.T. Askari, Cleveland Clinic, Cleveland, OH, USA

THE PREDICTOR AND PREDICTIVE VALUE ASSOCIATED WITH DISTAL EMBOLIZATION FOR THE PATIENTS WITH ST-ELEVATION MYOCARDIAL INFARCTION - VIRTUAL HISTOLOGY INTRAVASCULAR ULTRASOUND STUDY
R. Kawaguchi, S. Oshima, H. Hoshizaki, K. Taniguchi, Gunma Prefectural Cardiovascular Center, Maebashi, Japan

LYMPHOPENIA IN ACUTE PHASE OF ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION PREDICTS LONG-TERM REINFARCTION
J. Núñez, V. Bodí, J. Sanchis, L. Mainar, G. Miñana, P.Merlos, P. Palau, E. Rumiz, E. Núñez, A. Yacer, Universitat de Valencia, Valencia, Spain

ADP-INDUCED PLATELET AGGREGATION FREQUENTLY FAILS TO DETECT IMPAIRED CLOPIDOGREL-RESPONSIVENESS IN PATIENTS WITH CORONARY ARTERY DISEASE COMPARED TO A P2Y12-SPECIFIC ASSAY – INFLUENCE OF LOW HDL
A. Schaefer, S. Weinberger, G. Ertl, J. Bauersachs, University of Wuerzburg, Wuerzburg, Germany

MECHANISM OF THE REDUCED ASPIRIN ACTION IN PATIENTS AFTER CORONARY ARTERY BY-PASS SURGERY 
T. Mattiello, R. Guerriero, L.V. Lotti, E. Trifiro', B. Pucci, P. Gazzaniga, F. Caporuscio, C .Gaudio, L. Frati, F.M. Pulcinelli, Sapienza University of Rome, Rome, Italy

BACKWARDS INTO THE FUTURE OF MYOCARDIAL REGENERATION
W. Mohl, D. Milasinovic, S. Mina, B. Syeda, G. Weigel, H. Kasahara, K. Komamura, G. Heinze, Medical University of Vienna, Vienna, Austria

CLINICAL UTILITY OF GLUCOSE-INSULIN-POTASSIUM INFUSION IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION: A POOLED META-ANALYSIS OF RANDOMIZED CONTROLLED CLINICAL TRIALS
S.A. Saha, S. Katragadda, J. Molnar, R.R. Arora, Sacred Heart Medical Center, Spokane, WA, USA

PATIENTS WITH ISCHEMIC STROKE, INTRACRANIAL HEMORRHAGE, AND SUBARACHNOID HEMORRHAGE WITH INCREASED TROPONIN I LEVELS HAVE INCREASED HOSPITAL MORTALITY
R. Sandhu, W.S. Aronow, A. Rajdev, R. Sukhija, H. Amin, A. Sangha, New York Medical College, Valhalla, NY, USA

TRANSIENT AND PERSISTENT WORSENING RENAL FUNCTION IN SURVIVORS OF ACUTE MYOCARDIAL INFARCTION TREATED WITH PRIMARY ANGIOPLASTY
A. Goldberg, H. Hammerman, R. Beyar, M. Kapeliovich, W. Markiewicz, A. Roguin, D. Aronson, Sieff Government Hospital, Safed, Israel, Cardiology 

INCREASING TRENDS OF ACUTE MYOCARDIAL INFARCTION IN SPAIN: THE MONICA-CATALONIA PROJECT
S. Sans, A. Puigdefabregas, G. Paluzie, D. Monterde, I. Balaguer-Vintro, Institute of Health Studies, Barcelona, Spain

S22       Session
ATHEROSCLEROSIS: PRIMARY PREVENTION, HYPERTENSION, DIABETES MELLITUS, OBESITY, METABOLIC SYNDROME
Chairpersons:   S.S. Franklin, Irvine, CA, USA
                       D. Polk, Los Angeles, CA, USA
 

STATIN PLUS CHOLESTEROL ABSORPTION INHIBITION GIVES GREATER LDL
F.F. Samaha, N. Iqbal, D. Bregman, H. Ashfaq, M.M. Williams, University of Pennsylvania, Philadelphia, PA, USA

THE PRESENCE OF OBESITY IS STRONGLY ASSOCIATED WITH ESSENTIAL HYPERTENSION
M.R. Movahed, M. Jamal, M. Hashemzadeh, University of Arizona Sarver Heart Center, Southern Arizona VA Health Care System, Tucson, AZ, USA

IMPACT OF OBESITY ON MEASURES OF MORBIDITY AND MORTALITY IN PATIENTS UNDERGOING CORONARY ARTERY BYPASS GRAFTING
M. Alam, S.S. Virani, V. Nambi, V. Lee, M. Elayda, J.M. Wilson, C.M. Ballantyne, Baylor College of Medicine, Houston, Texas, USA

EFFECT OF REDUCTION OF IRON STORES ON VASCULAR AND CANCER OUTCOMES IN PATIENTS WITH PERIPHERAL ARTERIAL DISEASE (PAD): VA COOPERATIVE STUDY #410, THE IRON AND ATHEROSCLEROSIS STUDY (FEAST)
L.R. Zacharski, B.K. Chow, G.Shamayeva, P.W. Lavori, VA Medical Center, White River Jct., VT, Dartmouth Medical School, Lebanon, NH, USA

ADMINISTRATION OF GLUCOSE-INSULIN-POTASSIUM INFUSION IN ACUTE MYOCARDIAL INFARCTION DOES NOT REDUCE THE RISK OF CARDIOVASCULAR EVENTS AT ONE YEAR: A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS
S. Katragadda, S.A. Saha, R. Arora, J. Molnar, Chicago Medical School, North Chicago, IL, USA, Sacred Heart Medical Center, Spokane, WA, USA, University of Washington School of Medicine, Seattle, WA, USA

EFFECTS OF RECOMBINANT ACE2 GENE ON OXIDATIVE STRESS LEVELS IN HUMAN ENDOTHELIAL CELLS
J.C. Zhong, X.Y. Yu, Y. Huang, J.Y. Ye, Ningbo University, Ningbo, China

IMPACT OF COMPUTERIZED DECISION SUPPORT ON BLOOD PRESSURE MANAGEMENT AND CONTROL: A RANDOMIZED CONTROLLED TRIAL
L.S. Hicks, T. D. Sequist, J.Z. Ayanian, S. Shaykevich, D.F. Fairchild, E.J. Orav, D.W. Bates, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA

PL:03        Plenary Session
ARRHYTHMIA AND ELECTROPHYSIOLOGY/ CARDIAC PACING AND DEFIBRILLATION/CARDIAC RESYNCHRONIZATION THERAPY
Chairpersons:  M.E. Cain, Buffalo, NY, USA   
                      S.F. Nagueh, Houston, TX, USA
 

IMPACT OF NONINVASIVE TESTING ON IMPROVING IDENTIFICATION OF PATIENTS VULNERABLE TO SUSTAINED VENTRICULAR ARRHYTHMIAS (Invited Lecture)
M.E. Cain, University at Buffalo, Buffalo, NY, USA

CARDIAC RESYNCHRONIZATION THERAPY IN HEART FAILURE PATIENTS: HOW TO PREDICT RESPONDERS (Invited Lecture)
M.H. Pitzalis, East Carolina University, Greenville, NC, USA

DYSSYNCHRONY IN DIASTOLIC HEART FAILURE (Invited Lecture)
S.F. Nagueh, Methodist De Bakery Heart and Vascular Institute, TX, USA

HOW TO SELECT THE APPROPRIATE CANDIDATES FOR CARDIAC RESYNCHRONIZATION THERAPY (Invited Lecture)
M. Haghjoo, Iran University of Medical Sciences, Tehran, Iran

PSYCHOSOCIAL ADAPTATION AND QUALITY-OF-LIFE IN PATIENTS WITH PACEMAKERS AND IMPLANTABLE DEFIBRILLATORS (Invited Lecture)
F. Duru, University Hospital of Zurich, Zurich, Switzerland

CLINICAL CHARACTERISTICS AND RISK STRATIFICATION IN BRUGADA SYNDROME (Invited Lecture)
M. Takagi, Y. Sekiguchi, Y. Yokoyama, N. Aihara, K. Aonuma, M. Hiraoka, Osaka City University, Osaka, Japan

AN ATHLETE'S HEART MAY HARBOUR PROARRHYTHMIC CHANGES (Invited Lecture)
H. Heidbuchel, University of Leuven, Leuven, Belgium           

Long QT Syndrome: Should an ICD be Used? (Invited Lecture)
J.P. Daubert, University of Rochester Medical Center, Rochester, NY, USA          

UPDATE IN SYNCOPE MANAGEMENT. APPLICATIONS OF THE NEW GUIDELINES (Invited Lecture)
D. Flammang, La Croix Rousse University Hospital, Lyon, France       

DIAGNOSTIC AND PROGNOSTIC VALUE OF ECG CRITERIA FOR MYOCARDIAL INFARCTION IN COMPARISON WITH DELAYED-ENHANCEMENT MAGNETIC RESONANCE IMAGING (Invited Lecture)
R. Krittayaphong, Siriraj Hospital, Mahidol University, Bangkok, Thailand       

RISK STRATIFICATION WITH STRESS ECHOCARDIOGRAPHY (Invited Lecture)
A. Elhendy, Marshfield, WI, USA      

ASSESSMENT OF LEFT VENTRICULAR TORSION BY ECHOCARDIOGRAPHY: IS IT TIME TO DO THE TWIST? (Invited Lecture)
J.N. Bella, Bronx-Lebanon Hospital Center, Albert Einstein College of Medicine, Bronx, NY, USA

PROGNOSTIC VALUE OF CARDIOVASCULAR MAGNETIC RESONANCE IMAGING IN PATIENTS WITH ISCHEMIC HEART DISEASE (Invited Lecture)
V. Bodi, Hospital Clinico Universitario, Valencia, Spain

NEW ASPECTS OF ULTRASOUND CONTRAST IN CARDIOLOGY (Invited Lecture)
A.H. Jansen, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands

NON-INVASIVE ASSESSMENT OF VASCULAR LOAD AND VENTRICULAR-VASCULAR COUPLING: A FOCUS ON ECHOCARDIOGRAPHY (Invited Lecture)
J.A. Chirinos, University of Pennsylvania, VA Medical Center, Philadelphia, PA, USA

COMPARISON OF CARDIAC MDCT AND TEE IN DETECTING HIGH RISK EMBOLIC SOURCES
S.B. Ko, Y. Ko, J.H. Park, S.I Choi, EJ Chun, S.J Lee, M.K Han, H.J. Bae, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea

S23        Session
SECONDARY PREVENTION, MODIFICATION OF   LIPOPROTEINS, PROGNOSIS, RISK STRATIFICATION
Chairpersons:    Y. Birnbaum, Galveston, TX, USA
                        C.J. Chen, Houston, TX, USA

OMEGA-3-ACID ETHYL ESTERS REDUCES SMALL DENSE LOW DENSITY LIPOPROTEINS REGARDLESS OF THE BASELINE LIPID PROFILE
S.M. Attia, K.H. Nader, Tanta University, Tanta, Egypt

INADEQUATE ATTAINMENT OF RECOMMENDED LIPID LEVELS IN TREATED PATIENTS
G.A. Nichols, B.M. Ambegaonkar, V. Sazonov, J.B. Brown, Kaiser Permanente Center for Health Research, Portland, OR, USA

PROGNOSTIC SIGNIFICANCE OF INCIDENT COMPLETE LEFT BUNDLE BRANCH BLOCK OBSERVED OVER A 40-YEAR PERIOD
S. Seto, R. Imanishi, S. Ichimaru, E. Nakashima, M. Akahoshi, Nagasaki University, Nagasaki, Japan

IMPAIRED GLUCOSE TOLERANCE STRONGLY AND SIGNIFICANTLY INCREASES THE RISK OF FUTURE VASCULAR EVENTS IN ANGIOGRAPHIED CORONARY PATIENTS
H. Sourij, C.H. Saely, S. Aczel, H. Jahnel, R. Zweiker, T. Marte, G. Hoefle, W. Benzer, T.C. Wascher, H. Drexel, VIVIT Institute, Feldkirch, Austria

A SIMPLE PROGNOSTIC CLASSIFICATION MODEL FOR POST-PROCEDURAL COMPLICATIONS FOLLOWING PERCUTANEOUS CORONARY INTERVENTION FOR ACUTE MYOCARDIAL INFARCTION: RESULT BASED ON NEW YORK STATE PERCUTANEOUS CORONARY INTERVENTION DATABASE
A. Negassa, Albert Einstein College of Medicine, New York, USA

EFFECT OF ONCE WEEKLY ROSUVASTATIN ON LDL-C IN PATIENTS WITH PRIOR STATIN INTOLERANCE
J.M. Backes, J.F. Ruisinger, C.A. Gibson, P.M. Moriarty, Kansas University Medical Center (KUMC), Kansas City, KS, USA

HDL MORE THAN LDL: AN ACHIEVABLE GOAL
K.J. Reddy, J.R. Bangit, A.Z. Khan, M.S. Zaheer, Reddy Cardiac Wellness, Sugar Land, TX, USA

S24       Session
VASCULAR BIOLOGY, BASIC RESEARCH
Chairpersons:    S.B. Wheatcroft, Leeds, UK
                        P.K. Singal, Winnipeg, MB, Canada
 

OVEREXPRESSION OF CU/ZN-SUPEROXIDE DISMUTASE AND/OR CATALASE REDUCES BENZO(A)PYRENE-INDUCED ATHEROSCLEROSIS IN APOLIPOPROTEIN E-DEFICIENT MICE
Z. Guo, Meharry Medical College, TN, USA

THE ANGIOPOIETIN I +1602 A/T POLYMORPHISM ATTENUATES MICRORNA BINDING AND INCREASES RISK OF HEMORRHAGIC STROKE 
T. Yang, J. Chen, S. Yi, K. Sun, R.T. Hui, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China

THE CX3C CHEMOKINE FRACTALKINE ENHANCES VASCULAR DYSFUNCTION AND AGGRAVATES PLATELET ACTIVATION IN RATS WITH CHRONIC HEART FAILURE
A. Schaefer, C. Schulz, D. Fraccarollo, C. Schoepp, J.P. Frang, G. Ertl, S. Massberg, J. Bauersachs, University of Wuerzburg, Wuerzburg, Germany

CD40L IS UP-REGULATED BY TUMOR NECROSIS FACTOR IN PATIENTS WITH HEART FAILURE
P. Pignatelli, F. Violi, University of Rome La Sapienza, Rome, Italy

APOLIPOPROTEIN E-DEFICIENT LIPOPROTEINS INDUCE FOAM CELL FORMATION BY ACTIVATION OF UNFOLDED PROTEIN RESPONSES
H. Yang, Z. Guo, Meharry Medical College, TN, USA

THE EFFECTS OF RIVAROXABAN – AN ORAL, DIRECT FACTOR XA INHIBITOR – ON CLOT STRUCTURE AND DEGRADABILITY 
R. Varin, S. Mirshahi, P. Mirshahi, H. Li, G. Kierzek, J.F. Vigneau, E. Perzborn, M. Mirshahi, C. Soria, J. Soria,  Centre de Recherche des Cordeliers, Paris, France

DIFFERENCES BETWEEN NEW AND CLASSIC INTRAVENOUS IRON PREPARATIONS ON CARDIOVASCULAR TOXICITY IN NORMAL RATS
J.E. Toblli, G. Cao, L. Oliveri, M. Angerosa, Hospital Alemán, Buenos Aires, Argentina  

SYSTEMIC AND REGIONAL HEMODYNAMICS OF HYPOXIC PIGLETS TREATED WITH N^G-MONOMETHYL-L-ARGININE AFTER RESUSCITATION
T.F. Lee, C. Tymafichuk, P.Y. Cheung, University of Alberta, Edmonton, AB, Canada

ORAL L-ARGININE IS A REPAIRMAN BUT NOT AN ENHANCER OF ENDOTHELIAL FUNCTION: SYSTEMATIC REVIEW AND META-ANALYSIS
Y.Y. Bai, L. Sun, T. Yang, K. Sun, J.Z. Chen, R.T. Hui, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China

DIFFERENTIAL EXPRESSION OF FRACTALKINE AND MONONUCLEAR CELL RECRUITMENT BY HUMAN ARTERIAL OR VEIN ENDOTHELIAL CELLS STIMULATED WITH ANGIOTENSIN-II
M. Losada, L. Piqueras, C. Lopez-Gines, C. Company, C. Rius, M.J. Sanz, University of Valencia, Valencia, Spain

INTERLEUKIN-18 (IL-18), ENDOTHLINE-1 AND ALDOSTERONE INDUCE SMOOTH MUSCLE SENESCENCE VIA RHO-KINASE- AND PPAR- DEPENDENT PATHWAY
T. Akagami, T. Sakoda, T. Doi, T. Naka, T. Tsujino, T. Masuyama, M. Ohyanagi, Hyogo College of Medicine, Hyogo Japan

CHLAMYDIA INFECTION IN CARDIOVASCULAR PATHOLOGY: SEQUEL II
I.M. Petyaev, N.A. Zigangirova, Cambridge Theranostics Ltd., Cambridge, UK

PL:05        Plenary Session
THE RELEVANCE OF GENETICS IN PROVIDING AN
UNDERSTANDING OF CARDIOVASCULAR DISEASES
Chairpersons:     H. Boudoulas, Athens, Greece
                         K. Maiese, Detroit, MI, USA
 

GENETICS OF MYOCARDIAL INFARCTION (Invited Lecture)
R. Roberts, University of Ottawa Heart Institute, Ottawa, ON, Canada

GETTING TO THE POINT: FORKHEAD TRANSCRIPTION FACTORS IN THE VASCULAR SYSTEM (Invited Lecture)
K. Maiese, Wayne State University, Detroit, MI, USA